" Simply not hooking up" is more complicated than car weight vs front end weight. Our 1435 lb car has 320 lb front end weight.
If you are running a poweglide you may have too tight of a converter , the looser the stall, the easier it hits the tire , you might have too high a 1'st gear like 1.90-1.80, we have a 1.68 1'st gear, your engine combo could have a high torque set up, again it will hit the tire hard, you could be hitting the wheely bar and unloading the slicks, your slicks could be too old and hard. Also rim width makes a difference, we ran 10" wide on 12" wide slick [ max for our JF class] then moved to 11" rim , then again moved to 12" rim as I changed the power
And you thought you were asking an easy question ?