We adjust the spokes if there is more than 1/32" of up & down, or side to side run out. Make sure it's the wheel/ rim and not the tire, sometimes a tire does not get fully beaded to the rim. Front slicks are tricky.
If you have more run out than that you can send them to me or find a good motorcycle shop that can true your wheels, all tho not all M/C shop can true wheels. I have found dirt bike shops seem to know how to do true, HD shops not so much.
Jon